Bright light for nonseasonal depression?

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Bright light for nonseasonal depression?

A 58-year-old man’s condition was stable on a selective serotonin reuptake inhibitor (SSRI) after 3 major depressive episodes in 10 years. He disliked the idea of taking a drug for a long time and at one point took himself off the SSRI and started taking St. John’s wort. However, the reappearance of symptoms of depression soon led him to go back on the SSRI. As discussed in previous columns, on...

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Efficacy of light therapy in nonseasonal depression: a systematic review.

BACKGROUND The efficacy of bright light therapy is well established for winter depression but its status in depression without seasonal pattern is unclear. METHODS We systematically evaluated available data on the efficacy of light therapy in nonseasonal depression. RESULTS We identified 62 reports among which 15 met our predefined selection criteria. The available data show evidence for th...

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Bright light treatment in elderly patients with nonseasonal major depressive disorder: a randomized placebo-controlled trial.

CONTEXT Major depressive disorder (MDD) in elderly individuals is prevalent and debilitating. It is accompanied by circadian rhythm disturbances associated with impaired functioning of the suprachiasmatic nucleus, the biological clock of the brain. Circadian rhythm disturbances are common in the elderly. Suprachiasmatic nucleus stimulation using bright light treatment (BLT) may, therefore, impr...

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Bright light in elderly subjects with nonseasonal major depressive disorder: a double blind randomised clinical trial using early morning bright blue light comparing dim red light treatment

BACKGROUND Depression frequently occurs in the elderly. Its cause is largely unknown, but several studies point to disturbances of biological rhythmicity. In both normal aging, and depression, the functioning of the suprachiasmatic nucleus (SCN) is impaired, as evidenced by an increased prevalence of day-night rhythm perturbations, such as sleeping disorders. Moreover, the inhibitory SCN neuron...

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Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects.

Bright light therapy for seasonal affective disorder (SAD) has been investigated and applied for over 20 years. Physicians and clinicians are increasingly confident that bright light therapy is a potent, specifically active, nonpharmaceutical treatment modality. Indeed, the domain of light treatment is moving beyond SAD, to nonseasonal depression (unipolar and bipolar), seasonal flare-ups of bu...

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ژورنال

عنوان ژورنال: Journal of Psychiatry & Neuroscience

سال: 2011

ISSN: 1180-4882

DOI: 10.1503/jpn.110056